Immunofluorescent Studies on the Tumor Iuduced by Adenovirus Type 12
نویسندگان
چکیده
منابع مشابه
Electron microscopic studies on the tumor induced by adenovirus type 12.
Adenovirus 12-induced tumor has been so far considered to be an undifferentiated sarcoma, but in the present study it has been possible to obtain such electronmicroscopic findings that substantiate well the theory of the neuro-ectodermal supporting cell origin as suggested by the observation at optical level. In other words, a specific clinging picture of cellular membranes and the presence of ...
متن کاملImmunofluorescent Studies of Adenovirus 12 Tumors and of Cells Transformed or Infected by Adenoviruses
Complement-fixing (CF) antibody-positive sera from hamsters bearing adenovirus type 12 (Ad. 12)-induced tumors revealed specific immunofluorescent stainable antigens in essentially all Ad. 12 hamster tumor cells. The antigens were primarily in the form of cytoplasmic flecks; less frequent staining was seen as nuclear flecks or homogeneous staining of nucleus and cytoplasm of a small proportion ...
متن کاملImmunofluorescent Studies of the Potentiation of an Adenovirus-associated Virus by Adenovirus 7
A quantitative immunofluorescent procedure for detection of viral antigen was used to study the potentiation of AAV-1 by Ad.7. AAV viral antigen formed only when the cells were also infected with adenovirus, and only in cell culture systems in which the adenovirus infection proceeded to completion. Ad. 7 infection of AGMK. cell cultures did not potentiate AAV unless the Ad. 7 infection was itse...
متن کاملA Comparison of the Distribution of Tumors Produced by Intravenous Injection of Type 12 Adenovirus and Adeno-12 Tumor Cells1
Intravenous inoculation of IO6 adeno-12 tumor cells in 19 newborn hamsters resulted in multiple tumors distributed in 100% of the livers, kidneys, lungs, and adrenals. All but one heart contained tumors. Gonads, spleen, and pancreas also sup ported tumor growth but in less than half the animals. Tumors were even fewer in the intestine, thymus, muscles, bone mar row, and brain; in the latter thr...
متن کاملComplementation of human adenovirus type 5 ts mutants by human adenovirus type 12.
Temperature-sensitive mutants of type 5 adenovirus belonging to eight complementation groups were complemented in mixed infection by type 12 adenovirus, whereas mutants of 7 other groups were not enhanced. In some crosses, phenotypic mixing took place. No evidence of recombination between type 5 ts mutants and type 12 was found.
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 1967
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma1947.79.11-12_947